Method Development and Validation for Estimation of Eperisone Hydrochloride as API and in Tablet Dosage Form by Two Spectroscopic Methods
نویسندگان
چکیده
منابع مشابه
Development and Validation of Rp-hplc Method for Estimation of Atemoxetine Hydrochloride in Tablet Dosage Form
A RP-HPLC method was developed for the estimation of Atomoxetine Hydrochloride in tablet formulation, which is novel to the market. Chromatographic separation of the drug was achieved on a ENABLE C-18 G, 5μm, column (250 × 4.6 mm) using a mobile phase, Methanol: Ammonium phosphate buffer pH-3 (80:20 V/V) at a flow rate of 1ml/min. The drug eluted was monitored at 227 nm. The retention time was ...
متن کاملreversed phase high performance liquid chromatographic method for simultaneous estimation of eperisone hydrochloride and paracetamol in tablet dosage form
eperisone hydrochloride is a skeletal muscle relaxant and paracetamol is cyclooxygenase inhibitor. these drugs in combination are used as antispasmodics. a simple, specific, precise and accurate method was developed, namely reverse phase high performance liquid chromatography for simultaneous estimation of eperisone hydrochloride and paracetamol in tablet dosage form. in rp-hplc method separati...
متن کاملDevelopment and Validation of Uv Spectroscopic Method for the Determination of Metformin Hydrochloride in Tablet Dosage Form
A simple, economic, sensitive, precise and accurate UV spectrophotometric method was developed and validated for quantification of Metformin hydrochloride in bulk and in tablet dosage form. Adequate drug solubility and maximum assay sensitivity was found in 0.01N sodium hydroxide at 233nm. Calibration graph constructed at 233nm was linear in concentration range of 1-25μg/ml with correlation coe...
متن کاملDevelopment and Validation of Simultaneous Spectrophotometric Methods for Drotaverine Hydrochloride and Aceclofenac from Tablet Dosage Form
Two simple spectrophotometric methods have been developed for simultaneous estimation of drotaverine hydrochloride and aceclofenac from tablet dosage form. Method I is a simultaneous equation method (Vierodt's method), wavelengths selected are 306.5 and 276 nm. Method II is the absorbance ratio method (Q-Analysis), which employs 298.5 nm as λ(1) and 276 nm as λ(2) (λmax of AF) for formation of ...
متن کاملDevelopment and validation of a HPTLC method for Estimation of Duloxetine Hydrochloride in Bulk Drug and in Tablet Dosage Form
Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated silica gel 60 F254 aluminium plates using mixture of chloroform:methanol (8:1...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ISRN Analytical Chemistry
سال: 2013
ISSN: 2090-732X
DOI: 10.1155/2013/534763